UNIT 4

UNIT 4: Cell Communication & Cell Cycle Riedell Cells webpage Riedell AP BIO Cell Division webpage 9-11 Class Periods Exam Weight 10-15%

BIG IDEAS
1-EVO	Evolution
2-ENE	Energetics
3-IST	Information Storage and Transmission
4-SYI	Systems Interactions

SCIENCE PRACTICES
SP1	Concept Explanations
SP2	Visual Representations
SP3	Questions and Methods
SP4	Representing and Describing Data
SP5	Statistical Tests and Data Analysis
SP6	Argumentation

PowerPoints

Videos

LABS/Activities

BILL videos/Activities

The Cell Cycle

Regulation
IST 1.E.1; ENE 1.B.2

Meiosis

MITOSIS/MEIOSIS

Bozeman videos IST 1.B;1.C;
Phases of Mitosis
Phases of Meiosis
Meiosis
Meiosis Lab

Crossing over, linked genes, & Gene mapping IST 1.H.2; 1.H.3

Bozeman Mitosis Phases Google Docs quiz

IST1.B;1.C;

Desktop Mitosis cards IST 1.B;1.C;

Modeling mitosis with yarn IST 1.B;1.C;

LAB 7:Modeling Mitosis/Meiosis with Pop beads IST 1.B;1.C;

LAB 7: Mitosis/Meiosis Lab IST 1.B;1.C;
Sordaria lab LAB PIX

Interphase study guide
Check answers
IST 1.B.2; 1.D. 1 & 2

Mitosis study guide
Check answers

IST 1.B.2

BILL reverse prophase ? 1.B;1.C;

BILL mitosis roles ? 1.B;1.C;

BILL-SA/VOL Think about it ?'s

Crossing over, linked genes, & Gene mapping video
BILL genetic variation
IST 1.H.2; 1.H.3

Mitosis/Meiosis Comparison
IST 1.B.1; 1.C.1; 1.G

Past FRQs
REGULATION
CELL DIVISION

FUN
Cell division cartoons

REVIEWS
Mitosis/Meiosis Kahoot
Mitosis/Meiosis Card Review
Mitosis/Meiosis Clicker review w/answers

Big Idea	LO/EK description
The learning targets highlighted in yellow below are included in my CELLS UNIT
IST	3.A	Describe the ways that cells can communicate with one another.
IST	3.A.1	Cells communicate with one another through direct contact with other cells or from a distance via chemical signaling— a. Cells communicate by cell-to-cell contact.	POGIL-Cell Communication
IST	3.B	Explain how cells communicate with one another over short and long distances.
IST	3.B.1	Cells communicate over short distances by using local regulators that target cells in the vicinity of the signal-emitting cell — a. Signals released by one cell type can travel long distances to target cells of another cell type.	POGIL-Cell Communication
IST	3.C	Describe the components of a signal transduction pathway.
IST	3.C.1	Signal transduction pathways link signal reception with cellular responses.	MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS
IST	3.C.2	Many signal transduction pathways include protein modification and phosphorylation cascades.	MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS
IST	3.D	Describe the role of components of a signal transduction pathway in producing a cellular response.
IST	3.D.1	Signaling begins with the recognition of a chemical messenger—a ligand—by a receptor protein in a target cell— a. The ligand-binding domain of a receptor recognizes a specific chemical messenger, which can be a peptide, a small chemical, or protein, in a specific one-to-one relationship. b. G protein-coupled receptors are an example of a receptor protein in eukaryotes.	MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS
IST	3.D.2	Signaling cascades relay signals from receptors to cell targets, often amplifying the incoming signals, resulting in the appropriate responses by the cell, which could include cell growth, secretion of molecules, or gene expression— a. After the ligand binds, the intracellular domain of a receptor protein changes shape initiating transduction of the signal. b. Second messengers (such as cyclic AMP) are molecules that relay and amplify the intracellular signal. c. Binding of ligand-to-ligand-gated channels can cause the channel to open or close.	MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS
IST	3.E	Describe the role of the environment in eliciting a cellular response.
IST	E.1	Signal transduction pathways influence how the cell responds to its environment	POGIL-Cell Communication MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS BILL Cell signaling comparison
IST	3.F	Describe the different types of cellular responses elicited by a signal transduction pathway.
IST	3.F.1	Signal transduction may result in changes in gene expression and cell function, which may alter phenotype or result in programmed cell death (apoptosis).	MODELING SIGNAL TRANSDUCTION PATHWAYS CUTOUTS BILL Cell signaling comparison
IST	3.G	Explain how a change in the structure of any signaling molecule affects the activity of the signaling pathway.
IST	3.G.1	Changes in signal transduction pathways can alter cellular response— a. Mutations in any domain of the receptor protein or in any component of the signaling pathway may affect the downstream components by altering the subsequent transduction of the signal.	Effects of Changes in Pathways
IST	3.G.2	Chemicals that interfere with any component of the signaling pathway may activate or inhibit the pathway.	Effects of Changes in Pathways
ENE	3.A	Describe positive and/ or negative feedback mechanisms.
ENE	3.A.1	Organisms use feedback mechanisms to maintain their internal environments and respond to internal and external environmental changes.	Homeostatic Loops Homeostasis Hugs
ENE	3.B	Explain how negative feedback helps to maintain homeostasis.
ENE	3.B.1	Negative feedback mechanisms maintain homeostasis for a particular condition by regulating physiological processes. If a system is perturbed, negative feedback mechanisms return the system back to its target set point. These processes operate at the molecular and cellular levels.	Positive & Negative Feedback loops
ENE	3.C	Explain how positive feedback affects homeostasis.
ENE	3.C.1	Positive feedback mechanisms amplify responses and processes in biological organisms. The variable initiating the response is moved farther away from the initial set point. Amplification occurs when the stimulus is further activated, which, in turn, initiates an additional response that produces system change.	Positive & Negative Feedback loops
IST	1.B	Describe the events that occur in the cell cycle.
IST	1.B.1	In eukaryotes, cells divide and transmit genetic information via two highly regulated processes.	Mitosis/Meiosis Comparison
IST	1.B.2	The cell cycle is a highly regulated series of events for the growth and reproduction of cells— a. The cell cycle consists of sequential stages of interphase (G₁, S, G₂), mitosis, and cytokinesis. b. A cell can enter a stage (G₀) where it no longer divides, but it can reenter the cell cycle in response to appropriate cues. Nondividing cells may exit the cell cycle or be held at a particular stage in the cell cycle.	Regulation powerpoint Interphase study guide Phases of Mitosis Mitosis phases study guide
IST	1.C	Explain how mitosis results in the transmission of chromosomes from one generation to the next.
IST	1.C.1	Mitosis is a process that ensures the transfer of a complete genome from a parent cell to two genetically identical daughter cells— a. Mitosis plays a role in growth, tissue repair, and asexual reproduction. b. Mitosis alternates with interphase in the cell cycle. c. Mitosis occurs in a sequential series of steps (prophase, metaphase, anaphase, telophase).	Phases of Mitosis Mitosis phases study guide Mitosis/Meiosis Comparison
IST	1.D	Describe the role of checkpoints in regulating the cell cycle.
IST	1.D.1	A number of internal controls or checkpoints regulate progression through the cycle.	Interphase study guide
IST	1.D.2	Interactions between cyclins and cyclin dependent kinases control the cell cycle.	Interphase study guide
IST	1.E	Describe the effects of disruptions to the cell cycle on the cell or organism.
IST	1.E.1	Disruptions to the cell cycle may result in cancer and/or programmed cell death (apoptosis).	Powerpoint Regulation
		The following learning targets are from the CED for UNIT 5 Heredity
IST	1.F	Explain how meiosis results in the transmission of chromosomes from one generation to the next.
IST	1.F.1	Meiosis is a process that ensures the formation of haploid gamete cells in sexually reproducing diploid organisms	Modeling Mitosis/Meiosis with Pop beads
IST	1.G	Describe similarities and/ or differences between the phases and outcomes of mitosis and meiosis.
IST	1.G.1	Mitosis and meiosis are similar in the way chromosomes segregate but differ in the number of cells produced and the genetic content of the daughter cells.	Modeling Mitosis/Meiosis with Pop beads Mitosis/Meiosis Comparison
IST	1.H	Explain how the process of meiosis generates genetic diversity
IST	1.H.1	Separation of the homologous chromosomes in meiosis I ensures that each gamete receives a haploid (1n) set of chromosomes that comprises both maternal and paternal chromosomes.	Modeling Mitosis/Meiosis with Pop beads
IST	1.H.2	During meiosis I, homologous chromatids exchange genetic material via a process called “crossing over” (recombination), which increases genetic diversity among the resultant gametes.	Crossing over, linked genes, & Gene mapping video BILL genetic variation
IST	1.H.3	Sexual reproduction in eukaryotes involving gamete formation—including crossing over, the random assortment of chromosomes during meiosis, and subsequent fertilization of gametes—serves to increase variation.	Crossing over, linked genes, & Gene mapping video BILL genetic variation

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