AP CENTRAL FRQ's  2021       2019-1999        2020 Exam questions available in AP Classroom question bank

ANIMALS BODY SYSTEMS CELLS CELL DIVISION CELL SIGNALING
DNA RNA PROTEINS ECOLOGY  ENZYMES  EVOLUTION EXPERIMENTAL DESIGN
GENETICS GRAPHS/Math LABS METABOLISM MOLECULES
PLANTS PHOTOSYNTHESIS REGULATION RESPIRATION STRUCTURE & FUNCTION
TRANSPORT WATER Chi-Square    

DNA RNA PROTEINS

2021 #6            2021 All Questions      Scoring Guidelines          Sample Responses Q6
Gene expression
Temperature impact on protein folding
Identify data points explain data trend on graph
Support a hypothesis
Alternative splicing

2019 #1       2019 Free -Response Questions        Scoring Guidelines        Sample Responses Q1
Central Dogma
Effect of genetic mutation on pathway
Make a prediction/Justify
Feedback mechanisms
Mutualism
Evolutionary advantage

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2019 #6        2019 Free Response Questions            Scoring Guidelines          Sample Responses Q6
Genetic mutations
Experimental design
Provide reasoning to xplain  results
Make a prediction

2019 #7      2019 Free -Response Questions           Scoring Guidelines                     Sample Responses Q7
Glycolysis genes/proteins
mRNA Expression
Provide reasoning to explain chart

 
 

2018 #1       2018 Free-Response Questions            Scoring Guidelines            Sample Responses Q1  
Create a cladogram based on data
Estimate chronological time
Mitochondrial DNA analysis
Predict relatedness
Proteins vs DNA accuracy
Explain frequency of allele in population
Predict/Justify phenotypes
   

2018 #4  2018 All Free-Response Questions           Scoring Guidelines            Sample Responses Q4
Experimental controls
Explain graph/SEM
Gene mutation/pesticide resistance

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2017 #3      2017 Free Response Questions      SCORING GUIDELINES         Sample Responses Q3
Use codon chart to predict mutation
Impact of amino acid substitution
Mutations
Phenotype/genotype

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2017 #6       2017 Free-Response Questions         Scoring Guidelines              Sample Responses Q6
Apply content to new situation (comet assay)
Properties of DNA
Electrophoresis
Predict effect of mutagen
 

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2016 #1        2016 Free-Response Questions                Scoring Guidelines              Sample Responses Q1
Construct a bar graph
Effect of gene activity on tonicity
Predict/justify gene frequency

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2016 #4            2016 Free-Response Questions         Scoring Guidelines           Sample Responses Q4
Central Dogma
mRNA processing
Location of cellular pathways
Make a prediction

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2016  #6              2016 Free-Response Questions           Scoring Guidelines                Sample Responses Q6
cDNA
Experimental design
Ecosystem sampling
Explain results/Provide reasoning

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2015 #7   2015 ALL Questions             Scoring Guidelines       Sample Responses Q7
Smell perception
Transmission of signal across synapse
Explain results of gene expression

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2014 #5.              2014 Free-Response Questions            Scoring Guidelines              Sample Responses Q5 
GMO's

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2014 # 2014 All questions            Scoring Guidelines          Sample Responses Q8
Mutations in genetically engineered flies
Mechanisms leading to genetic variation
Role of genetic variation in evolution
Provide evidence

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2013 #5   2013 Free-Response Questions            Scoring Guidelines              Sample Responses Q5 
Mutations
Compare codon data from table

Explain genetic change in organisms
Predict/explain structure/function changes in protein

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2012 #3   2012 All questions           Scoring Guidelines                   Sample Responses Q3
Role of following in regulation of protein synthesis
~ RNA Splicing
~ repressor proteins
~mtehylation
~ siRNA
Types of
mutations/effect on protein synthesis
Environmental causes of mutations/effect on genome
Epigenetics

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2010 B #2             2010 B All Questions                 Scoring Guidelines                 Sample Responses Q2 
Mutations/imapct on protein sructure/function
Frequency of alleles in population

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2010 B #3           2010 B All Questions                 Scoring Guidelines            Sample Responses Q3
Bacterial roles in ecosystems
Genetically modified organisms

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2010 B #4           2010 B All Questions                 Scoring Guidelines            Sample Responses Q4

Abiotic/biotic factors
Experimental design
Support hypothesis with data
Describe experimental modifications

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2009 #4               2009 All Questions                  Scoring Guidelines                   Sample Responses Q4
Role of following in protein synthesis:
~ RNA polymerase
~ Spliceosomes (snRNPs)
~ Codons
~ Ribosomes
~ tRNA
Regulation of protein synthesis/activity
Central Dogma
Viruses

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2008 B #2 2008 All Questions      Scoring Guidelines       Sample Responses Q2
Structure function
Organization of subunits into:
~ A eukaryotic chromosome
~ mature angiosperm root
~ a colony of bees
~ An inner membrane of a mitochondrion
~ An enzyme

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2007 #4.               2007 All Questions                  Scoring Guidelines                Sample Responses Q4
Construct plasmid map from DNA sequencing diagram
Recombinant DNA technology (plasmid transformation)
Benefits/threats of GMO's

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2007B  #3  2007B All  Questions        Scoring Guidelines        Sample Responses Q3
mRNA processing
Translation
Protein secretion pathway

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2006 #1              2006 All Questions                   Scoring Guidelines             Sample Responses Q1
Eukaryotic organelles structure/function
Prokaryotes/Eukaryotes differences
DNA
Ribosomes
Cell Wall
Endosymbiotic theory
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2006B #2            2006 B All Questions           Scoring Guidelines         Sample Responses Q2 
Impact of structure on function of:
~ enyzme/catalysis
~ RNA/protein synthesis
~ cell membranes/signal transduction
~ membrane proteins/facilitated diffusion & active transport


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2005 #2.          2005 All Questions                   Scoring Guidelines               Sample Responses
Structure/function eukaryotic chromosome
Eukaryotes/prokaryote differences
Evolutionary significance


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2005 B #3          2005 B All Questions        Scoring Guidelines           Sample Responses
Compare/contrast transcription/translation
Post translational protein modification
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2004 #2   2004 Questions                 Scoring Guidelines       Sample Responses Q2        
Provide supporting evidence for:
~nonconstancy of species
~Branching evolution/common descent
~Gradual changes in species
~Natural selection
Modifications in Darwin's theory due to:
Hardy-Weinberg equilbrium
Punctuated equilbrium
Genetic engineering

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2003 B #1.        2003 B All Questions          Scoring Guidelines        Sample Responses Q1  
Compare:
Prokaryote/Eukaryote genetic material
Replication of DNA
Transcription/translation
Gene regulation
Cell division


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2002 #1           2002 All Questions                 Scoring Guidelines             Sample Responses Q1
PCR
Plasmids
DNA RFLP analysis

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2002B #3         2002 B All Questions             Scoring Guidelines            Sample Responses Q3
Structure/function
~ tubulin : myosin
~ cellulose : chitin
~ messenger RNA : transfer RNA

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2001 #4       2001 All Questions                Scoring Guidelines                Sample Responses Q4
Protein structure
Roles of DNA/RNA in protein synthesis
Roles of proteins in membrane structure/transport


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2000 #3.       2000 All Questions               Scoring Guidelines            Sample Responses Q3
Information transfer
Mitosis
Transcription/translation
Transformation/transduction/conjugation

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1999 #4         1999 All Questions                Scoring Guidelines             Sample Responses Q4
DNA
Experimenal evidence
 

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