AP CENTRAL FRQ's
2023 2022-1999 2020 Exam questions available in AP Classroom question bank
MOLECULES
2021#2
2021
All Questions
Scoring Guidelines
Sample Responses Q2
Pedigrees
Mutations
Glucose structure/bonding
Glucose metabolism
Mitochondrial inheritance
Construct a graph from data
Make a prediction/Justify with data
2021 #6
2021
All Questions Scoring Guidelines coming
after exams are scored
Gene expression
Temperature impact on protein folding
Identify data points/explain trend on graph
Support a hypothesis
Alternative splicing
2017 #3
2017 All Free-Response Questions
Scoring
Guidelines
Sample Responses Q3
Use codon chart to predict mutation
Impact of amino acid substitution
Mutations
Phenotype/genotype
2017 #6
2017 All Free-Response Questions
Scoring Guidelines
Sample Responses Q6
Apply content to new situation (comet assay)
Properties of DNA
Electrophoresis
Predict effect of mutagen
2017 #7
2017 ll Free-Response Questions Scoring
Guidelines
Sample Responses Q7
pH
Anaerobic/Aerobic respiration
Natural selection
Predict impact of environmental change on populations
2017 #8
2017 All Free-Response Questions
Scoring Guidelines
Sample Responses Q8
Hydrophobic hormones
Cell membranes
Structure/Function
Hormones/cell signaling
Antibodies/Immune system
2013
#5
2013 All questions
Scoring Guidelines
Sample Responses Q5
Mutation
Predict effects on structure/function of protein
2008 #1
2008 All Questions
Scoring Guidelines
Sample Responses Q1
Bonds/interactions in proteins
How protein structure impacts function in
~ muscle contraction
~ Regulation enzyme activity
~ Cell signaling
Sickle cell hemoglobin mutation
Heterozygote advantage
2008 B #2
2008 B All Questions
Scoring Guidelines
Sample Responses Q2
Structure/function
Organization of subunits into:
~ A eukaryotic chromosome
~ mature angiosperm root
~ a colony of bees
~ An inner membrane of a
mitochondrion
~ An enzyme
2005 #2
2005 All Questions
Scoring Guidelines
Scoring Commentary
Sample Responses Q2
Structure/function eukaryotic
chromosome
Eukaryotes/prokaryote differences
Evolutionary significance
2002B #3
2002B All Questions
Scoring Guidelines
Sample Responses Q3
Structure/function
~ tubulin : myosin
~ cellulose : chitin
~ messenger RNA : transfer RNA
2001 #4
2001 All Questions
Scoring Guidelines
Sample Responses Q4
Composition/levels of structure in proteins
Roles of DNA/RNA in protein synthesis
Roles of proteins in membrane structure/transport
(1996) The
unique properties (characteristics) of water make life possible on Earth.
Select three properties of water and:
a. for each
property, identify and define the property and explain it in terms of the
physical/chemical nature of water.
b. for each property, describe
one example of how the property affects the functioning of living
organisms.
(1991)
Carbon is a very important element in living systems.
a. Describe the
various characteristics of the carbon atom that make possible the building of a
variety of biological molecules.
b. Explain how
reactions involving carbon-containing compounds can contribute to the greenhouse
effect.
c.
The following structures are examples of two different categories of
biological compounds.
Describe how each category of compounds is important to
the structure and functions of living systems.
Category I
Category II
A drawing of a phospholipid*
A drawing of an amino acid
*Drawings not available
(1994) Enzymes are
biological catalysts.
a. Relate the
chemical structure of an enzyme to its specificity and catalytic activity.
b. Design a
quantitative experiment to investigate the influence of pH
or temperature on the activity
of an enzyme.
c.
Describe what information concerning the structure of an enzyme could be
inferred from your experiment.
a. Carbohydrates
b. Proteins
c. Lipids
d. Nucleic Acids
(1978) Give specific examples to
illustrate the theory of enzyme action, and include in your discussion the
effects of each of the following:
a. Substrate
concentration
b. pH shifts
c.
Temperature shifts
d.
Competitive inhibition.
(1975) Describe the
chemical compositions and configuration of enzymes and discuss the factors that
modify enzyme structure and/or function.
1973) Hypotheses derived
from laboratory experiments and field observations have been advanced to explain
the origin of life on earth. Starting with a probable prelife environment,
describe the formation and evolution of the various trophic forms (nutrition
types) to and including unicellular organisms. Describe at least one experiment
whose results support one of these scientific hypotheses.
(1972) A class of biology
students performed an experiment on the digestion of starch by salivary amylase.
Each student determined the length of time required for different dilutions of
his saliva to digest completely a standard concentration of starch. Iodine was
used to test for the presence of starch. The results obtained by some of the
class are summarized in the table below.
TIME REQUIRED FOR THE DISAPPEARANCE OF STARCH WITH VARIOUS SALIVA DILUTIONS(saliva: H2O)
Student
1:9 (10%)
1:19 (5%)
1:49 (2%)
1:99 (1%)
A
45 seconds
50 seconds
100 seconds 135 seconds
B
(no end point)
C
90 seconds
100 seconds
200 seconds 270 seconds
D
260 seconds
300 seconds
600 seconds 800 seconds
a. Present
the data for Student A in graphic form.
b. Carefully
examine the data collected by the four students above and state as many
conclusions as you can that are supported by these data.
c. Assuming
there have been no errors in techniques, form as many hypotheses as you can to
explain the differences observed.
d. Design
one experiment to test the validity of one hypothesis. Clearly state what data
you would want to collect in this experiment to test your hypothesis.
(1969) Proteins
functioning as enzymes exhibit precise specifications. Discuss the levels of
structural organization within proteins which are responsible for specific
molecular interaction.
(1968) Suppose that you
have isolated an extract from a tissue and you have found that the extract
speeds up the rate of a particular reaction. What kind of information would you
need to demonstrate that the substance responsible for increasing the rate of
this reaction is an enzyme? Explain how this information would indicate that the
catalytic effect is due to an enzyme.
1965:
Biologists and biochemists have made outstanding progress within the past
quarter century in elucidating principles
and structures which govern the activities of living matter.
|
These areas of progress include:
A. The structure and code of the DNA
molecule
B. The use of radioactive
isotopes as tracers in biological processes
C. The citric acid cycle and its
relationship to mitochondria
D. The use of electron microscopy in
revealing the structure of the cell
Discuss any one of these developments and its impact on biological thought and
progress.
Your answer should include:
a. a brief account of the
development
b.
the names of the most prominent investigators involved
c.
the nature of its impact on biology